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Reviews

Systems Medicine in Colorectal Cancer: From a Mathematical Model Toward a New Type of Clinical Trial

September 5, 2016August 2, 2017 Publications, Reviews
In this review, we primarily focus on and aim towards combination therapies with targeted drugs: inhibitors of signaling proteins affected by excess of function.

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Clinical implications of omics and systems medicine: focus on predictive and individualized treatment

August 28, 2015August 28, 2015 Publications, Reviews
The aims of this review are to provide a brief introduction to systems medicine and discuss how it may contribute to the clinical implementation of individualized treatment, using clinically relevant examples.

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Modules, networks and systems medicine for understanding disease and aiding diagnosis

May 29, 2015July 28, 2015 Publications, Reviews
This review explains and provides examples of how network-based analyses of omics data, in combination with functional and clinical studies, are aiding our understanding of disease, as well as helping to prioritize diagnostic markers or therapeutic candidate genes.

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Featured Articles

October 24, 2016January 9, 2017 Featured Articles, Project Interviews, Projects

Project Interview: Systems Medicine of Mitochondrial Parkinson’s Disease – SysMedPD

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February 24, 2016February 24, 2016 10 Questions to ..., Featured Articles

Interview with Prof. Erwin Böttinger, Chief Executive Officer Berlin Institute of Health (BIH)

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February 22, 2016 Featured Articles, Project Interviews, Projects, Publications, Research projects

Project Interview: Exploiting MELanoma disease comPLEXity – MEL-PLEX

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January 29, 2016February 1, 2016 10 Questions Science, Featured Articles, Publications

10 Questions Science: The first Systems Medicine book

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January 20, 2016February 1, 2016 10 Questions Science, Featured Articles, Publications

10 Questions Science: Personalised modelling predicts neuroblastoma survival

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January 18, 2016January 18, 2016 Featured Articles, Project Interviews, Projects, Publications, Research projects

Project Interview: Personalizing health care in Multiple Sclerosis using systems medicine tools – Sys4MS

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January 15, 2016January 15, 2016 Featured Articles, Other initiatives, Project Interviews, Projects, Publications

Project Interview: Avicenna – A strategy for In Silico Clinical Trials/Avicenna

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December 16, 2015December 16, 2015 Featured Articles, Project Interviews, Projects, Publications, Research projects

Project Interview: Combination therapy and biomarkers for Multiple Sclerosis – CombiMS

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December 7, 2015February 1, 2016 10 Questions to ..., Featured Articles, Publications

10 Questions to Prof Olaf Wolkenhauer

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November 24, 2015January 12, 2016 10 Questions Science, Featured Articles, Publications

10 Questions Science: Detection of diseases before symptoms arise

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November 18, 2015November 18, 2015 Featured Articles, Other initiatives, Project Interviews, Projects, Publications

Project Interview: Profiling Responders In Antibody Therapies (PRIAT)

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THE SYSTEMS MEDICINE WEB HUB
Systemsmedicine.net is the home of systems medicine in the Internet. An initiative of the European Commission (DG Health Research), the Projekttraeger Juelich (PTJ) and the Federal German Ministry for Education and Research (BMBF). The Systems Medicine Web Hub supports researchers with the communication of their efforts to improve the diagnosis, prognosis and therapy of diseases. More...
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