“Constructing and validating systems modeling tools as novel prognostic markers in melanoma”
Building on prototype tools, we will develop mathematical models of autophagy signalling and will analyse autophagic processes in clinical samples of primary melanoma by quantitative immuno-histochemistry. In addition, quantitative biochemical data will be collected from in vitro melanoma cultures. Mathematical modelling techniques, including deterministic and data-driven modelling approaches, will be applied to develop and validate an innovative prognostic systems-biomarker panel for patients diagnosed with early stage melanoma. Through associated projects, additional data may become available for further analysis and modelling tasks. Research and Training Secondments to international academic and private sector partner are a central component of the programme. The project is funded by the European Union through MEL-PLEX, a pan-European academic/private sector research training network in the fields of Cancer Cell Biology, Translational Cancer Research and applied Systems Biology/Systems Medicine.
Recruited researchers must participate in training courses and events organised by the network. These aim to develop key research and transferable skills to allow researchers to navigate confidently between academic, clinical and private sector research environments.
Host institution: The University of Stuttgart is one of the top nine leading technical universities in Germany.
The position is available from April 1st 2016, initially for 2 years, with the possibility for extension.
Applications must be received by 29th of February 2016, 5pm (GMT).